The cream for cryopreservation of cells will protect the skin from frostbite

Researchers from the Indian Academy of Sciences have adapted the laboratory technology of cryopreservation of cells for use against frostbite of the skin on the street. An experimental cream called SynAFP allows skin cells to maintain integrity during freezing, which significantly reduces the risk of frostbite.

In cryopreservation, it is extremely important to prevent the formation of ice crystals inside living tissues, because sharp and hard ice destroys them. To do this, the substance dimethyl sulfoxide (DMSO) is used, which acts inside the cell, in combination with polyvinyl alcohol (PVA) is used, which protects the cell membranes from ice outside. Experimentally, Indian scientists have selected a composition that is suitable for use on open skin.

In practical tests, the survival rate of SynAFP-treated cells reached 80%. Alas, this does not exclude the very fact of frostbite, only reduces the extent of damage, and the wounds are healed faster. But the cream has a fundamental drawback: it disappears from the skin too quickly. If you apply it 15 minutes before going out into the cold, the protection will work, but after 30 minutes its effect will go to zero. Probably, the cream will need to be applied often, which casts doubt on its practicality.